Breast tumors: an overview
نویسندگان
چکیده
Benign epithelial lesions with no significant tendency to malignant transformation include: adenoma: -Ductal -lactating -Tubular adenosis: -apocrine -blunt duct -microglandular -sclerosing fibroadenoma radial scar/complex sclerosing lesions Invasive breast carcinomas are divided into two major categories on the basis of their cytoarchitectural features: Invasive ductal carcinoma: -acinic cell carcinoma -adenoid cystic carcinoma -apocrine carcinoma -cribriform carcinoma -glycogen-rich/clear cell -inflammatory carcinoma -lipid-rich carcinoma -medullary carcinoma -metaplastic carcinoma -micropapillary carcinoma -mucinous carcinoma -neuroendocrine carcinoma -oncocytic carcinoma -papillary carcinoma -sebaceous carcinoma -Secretory Breast Carcinoma -tubular carcinoma lobular carcinoma -pleomorphic -signet ring cell The recognized precursor lesions of invasive breast carcinoma are: intraductal proliferative lesions: -atypical ductal hyperplasia -ductal carcinoma in situ -florid -usual lobular neoplasia/atypical lobular. The terminology Invasive ductal/lobular carcinoma does not imply an origin form ducts and lobules, respectively, but the presence of cytoarchitectural and phenotypical features of ductal-type and lobular-type, respectively. Ductal adenocarcinoma is the most common. Lobular carcinoma is the second malignant breast tumour. Medullary carcinoma is rare. Hyperplasia is a proliferation without criteria of malignancy. Fibroadenomas are benign breast tumours.
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